Chemical Research Letters, May 2021. Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis, and research on the structure and performance of functional materials. In an article, author is Hameed, Afaf M. Abdel, once mentioned the application of 23814-12-2, Name is 1H-Benzo[d][1,2,3]triazole-5-carboxylic acid. Now introduce a scientific discovery about this category, Application In Synthesis of 1H-Benzo[d][1,2,3]triazole-5-carboxylic acid.
Many methods to prepare heterocyclic compounds involve toxic solvents and reagents. There is therefore a need to design cleaner synthetic procedures. 1,6-Naphthyridine derivatives are used in many applications such as cancer chemotherapy, antibacterials, antivirals and antiproliferatives. Here, we report the solvent-free and catalyst-free synthesis of 1,6-naphthyridine derivatives. Synthesis is done by grinding of 2 mmol of ketones, 2 mmol of malononitrile and 1 mmol of amines in a mortar at room temperature for 5-7 min. 1,2-Dihydro[1,6]-naphthyridine derivatives were obtained in 90-97 % yields.
Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. Welcome to check out more blogs about 23814-12-2, in my other articles. Application In Synthesis of 1H-Benzo[d][1,2,3]triazole-5-carboxylic acid.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem