Chemical Research Letters, May 2021. Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis, and research on the structure and performance of functional materials. In an article, author is Pirnat, Klemen, once mentioned the application of 96-49-1, Name is Ethylene carbonate. Now introduce a scientific discovery about this category, SDS of cas: 96-49-1.
A simple three step synthesis of aminosubstituted 1,2,7,8-tetrahydro-2,7-naphthyridine-4-carboxylates is described. Ethyl (3-cyano-6-ethoxy-2-oxo-1,2-dihydropyridin-4-yl)acetate 3, formed by the condensation of diethyl acetone-1,3-dicarboxylate with malononitrile, was transformed with N,N-dimethylformamide dimethylacetal (DMFDMA) into (E)-ethyl 2-(3-cyano-6-ethoxy-2-oxo-1,2-dihydropyridin-4-yl)-3-(dimethylamino)propenoate 4. In further reaction the dimethylamino group was substituted with amino, hydroxy or substituted hydrazino group, followed by cyclisation to afford substituted 1-amino-7,8-dihydro-2,7-naphthyridine-4-carboxylate 6b, 1-imino-7,8-dihydro-1H-pyrano[3,4-c]pyridine-4-carboxylate 8, and 1-imino-2aminosubstituted 1,2,7,8-tetrahydro-2,7-naphthyridine-4-carboxylates 13a-i.
Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. Welcome to check out more blogs about 96-49-1, in my other articles. SDS of cas: 96-49-1.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem