Chemical Research Letters, May 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. , Application In Synthesis of 2-Methylcyclohexa-2,5-diene-1,4-dione, 553-97-9, Name is 2-Methylcyclohexa-2,5-diene-1,4-dione, molecular formula is C7H6O2, belongs to naphthyridine compound. In a document, author is Sharma, Kamlesh, introduce the new discover.
Background: Protein farnesyltransferase (PFT) inhibitors have emerged as a potent target for the malaria treatment caused by the Plasmodium falciparum (Pf) parasite. Objective: To explore the various scaffolds which are active against Pf-PFT target. Result: Seven inhibitor scaffolds based on ethylenediamine, peptidomimetic, benzophenone, benzamide, tetrahydroquinoline, naphthyridine and oxy-tetrahydroquinoline, have been developed till date. Conclusion: It is concluded that naphthyridine based drugs are the most promising one. Furthermore, introducing the hydrophobic molecules like isoprenyl groups to a protein or a chemical compound facilitate protein-protein and protein-membrane interactions thereby makes them good candidates as new therapeutics. The future research should focus on the disease rather than the infection and the dynamics of its transmission; this will bring a new vision about the disease.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. I hope my blog about 553-97-9 is helpful to your research. Application In Synthesis of 2-Methylcyclohexa-2,5-diene-1,4-dione.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem