New Advances in Chemical Research in 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. In an article, author is Chen Xiu-Wen, once mentioned the application of 126-30-7, Name is 2,2-Dimethylpropane-1,3-diol, molecular formula is C5H12O2. Now introduce a scientific discovery about this category, SDS of cas: 126-30-7.
title compound (14S)-2,14-diphenyl-6,6a,11,12-tetrahydro-5H,10H,14H-[1,8]naphthyridino[1,2-c]pyrido[3,2,1-ij]quinazoline-3-carbonitrile (C31H26N4, M-r = 454.56) has been synthesized with 2-aminonicotinaldehyde and 3-oxo-3-phenylpropanenitrile as starting materials, and its crystal structure was determined by single-crystal X-ray diffraction for the first time. The crystal belongs to the triclinic system, space group P (1) over bar with a = 8.5833(8), b = 11.9168(12), c = 14.4424(14) angstrom, alpha = 84.208(3)degrees, beta = 88.427(3)degrees, gamma = 73.704(3)degrees, V= 1410.7(2) angstrom(3), Z = 2, F(000) = 480, mu = 0.064 mm(-1), S = 0.966, the final R = 0.0484 and wR = 0.1388 for 5041 observed reflections with I > 2 sigma (I) and 316 variable parameters. The preliminary biological tests show that the title compound has a good antitumor activity against K562 in vitro.
The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. In my other articles, you can also check out more blogs about 126-30-7. SDS of cas: 126-30-7.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem