Brief introduction of 1118-61-2

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1118-61-2, Name is 3-Aminocrotononitrile, molecular formula is C4H6N2, belongs to naphthyridine compound, is a common compound. In a patnet, author is Zhao, Qun, once mentioned the new application about 1118-61-2, Computed Properties of C4H6N2.

One-Pot Four-Component Synthesis of 5,10-Diarylpyrido[4,3-b][1,6] Naphthyridine Derivatives in Ionic Liquids Catalyzed by TsOH

A one-pot four-component reaction of aldehyde, aromatic amine, and two equivalents of piperidine-2,4-dione was treated in ionic liquids of [BMIm]Br catalyzed by TsOH (p-toluenesulfonic acid), and gave a series of 5,10-diarylpyrido[4,3-b][1,6]naphthyridine derivatives in good yields. This procedure has the advantages of mild reaction conditions, good yields, one-pot, and environmentally benign.

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Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem