In an article, author is Mogilaiah, K., once mentioned the application of 1689-64-1, Recommanded Product: 1689-64-1, Name is 9H-Fluoren-9-ol, molecular formula is C13H10O, molecular weight is 182.22, MDL number is MFCD00001135, category is naphthyridine. Now introduce a scientific discovery about this category.
AN EFFICIENT SYNTHESIS OF 2-(2-SUBSTITUTED [1,8] NAPHTHYRIDIN-3-YL)-5-(SUBSTITUTED 2-FURYL)-1,3,4-OXADIAZOLES USING PhI(OAc)(2)-Al2O3 IN THE SOLID STATE AND EVALUATION OF THEIR BIOLOGICAL ACTIVITY
A simple and eco-friendly method for the synthesis of 2-(2–substituted [1,8] naphthyridin-3-yl),5-(substituted 2-furyl)-1,3,4-oxadiazoles 4 has been developed by the oxidation of the corresponding N3-[1-(5-nitro-2-furyl) methylidene]-2-methyl [1,8] naphthyridine-3-carbohydrazide 3 with alumina-supported iodobenzene diacetate [PhI(OAc)(2)-Al2O3] the solid state at RT under grinding conditions. The structural assignments of compounds 3 and 4 are based on their elemental analyses and spectral (IR, H-1 NMR and MS) data. The compounds 4 have been tested for their antibacterial and anti-inflammatory activities.
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Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem