Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, Product Details of 99-09-299-09-2, Name is 3-Nitroaniline, SMILES is NC1=CC=CC([N+]([O-])=O)=C1, belongs to naphthyridine compound. In a article, author is Wang, Dao-Lin, introduce new discover of the category.
An efficient synthesis of benzo[b]benzofurano[2,3-e][1,6]naphthyridine-8-ones
An efficient method for the synthesis of benzo[b]benzofurano[2,3-e][1,6]naphthyridine-8-one derivatives has been developed via Pictet-Spengler reaction of 4-(3-aminobenzofuran-2-yl)quinoline-2-ones, which could be obtained from alkylation of 4-bromomethylquinoline-2-ones with salicylonitrile and subsequent Thorpe-Ziegler isomerization, with aromatic aldehydes under p-TsOH as catalyst in good yields. (C) 2014 Dao-Lin Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. All rights reserved.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 99-09-2. Product Details of 99-09-2.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem