Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 99-09-2, Name is 3-Nitroaniline, SMILES is NC1=CC=CC([N+]([O-])=O)=C1, belongs to naphthyridines compound. In a document, author is Kumar, Vivek, introduce the new discover, HPLC of Formula: C6H6N2O2.
Anticancer and immunomodulatory activities of novel 1,8-naphthyridine derivatives
A number of 1,8-naphthyridine derivatives (22-62) have been synthesized and screened for their in vitro cytotoxicity against eight tumors and two non-tumor cell lines. Halogen substituted 1,8-naphthyridine-3-caboxamide derivatives showed potent activity with compound 47 having IC(50) of 0.41 and 0.77 mu M on MIAPaCa and K-562 cancer cell lines, respectively while, compound 36 had IC(50) of 1.19 mu M on PA-1 cancer cell line. However, one of the unsubstituted 1,8-naphthyridine-C-3′-heteroaryl derivative 29 showed potent cytotoxicity with IC(50) of 0.41 and 1.4 mu M on PA-1 and SW620 cancer cell lines, respectively. These compounds were also evaluated for anti-inflammatory activity as suggested by downregulation of proinflammaotory cytokines.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 99-09-2 is helpful to your research. HPLC of Formula: C6H6N2O2.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem