Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 13822-56-5, Name is 3-(Trimethoxysilyl)propan-1-amine, molecular formula is , belongs to naphthyridines compound. In a document, author is Lu, Yihuan, Recommanded Product: 3-(Trimethoxysilyl)propan-1-amine.
A novel naphthyridine tetramer that recognizes tandem G-G mismatches by the formation of an interhelical complex
We have designed and synthesized a novel naphthyridine tetramer, p-NCTB, for the recognition of tandem guanine-guanine (G-G) mismatches in DNA. p-NCTB possesses a p-biphenyl linker connecting two naphthyridine carbamate dimer (NCD) moieties that recognize G-G mismatches. p-NCTB preferentially bound to tandem G-G mismatches in dCGGG/dCGGG over dCGG/dCGG. Two dCGGG/dCGGG sites were simultaneously recognized and were noncovalently cross-linked via the formation of inter- and intrastrand complexes with p-NCTB. The intrastrand binding was more favorable, which could allow p-NCTB to bind selectively to a sequence containing multiple dCGGG/dCGGG sites.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 13822-56-5, in my other articles. Recommanded Product: 3-(Trimethoxysilyl)propan-1-amine.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem