Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 126-30-7, Name is 2,2-Dimethylpropane-1,3-diol. In a document, author is Shatsauskas, Anton L., introducing its new discovery. Safety of 2,2-Dimethylpropane-1,3-diol.
Rearrangement of 7-Aryloxazolo[5,4-b]pyridines to Benzo[c][1,7]naphthyridine-4(3H)-ones and Thieno[3,2-c][1,7]naphthyridine-6(7H)-ones
In this work, we describe the development of the rearrangement for 7-aryl-substituted oxazolo[S,4-b]pyridines treated with aluminum chloride into synthetically hard-to-reach benzo[c][1,7]naphthyridinones. The discovered rearrangement is applied to a variety of electron-rich (hetero)arene substrates. It offers the advantages of mild conditions (90 degrees C temperature), fast reaction rates (<4 h), compatibility with air moisture, and the use of inexpensive commercial reagents. The proposed reaction mechanism and key elementary reaction acts were studied in detail using quantum chemical calculations. The photophysical properties of the synthesized compounds were studied by steady-state UV-vis spectroscopy. I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 126-30-7 help many people in the next few years. Safety of 2,2-Dimethylpropane-1,3-diol.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem