One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 106-49-0, Name is p-Toluidine, formurla is C7H9N. In a document, author is Wang, Dao-Lin, introducing its new discovery. Computed Properties of C7H9N.
Synthesis of novel benzo[b]pyrimido[4 ‘,5 ‘:5,4]thieno[2,3-e][1,6]naphthyridine-8-ones via Pictet-Spengler cyclization
An efficient method for the synthesis of novel benzo[b]pyrimido[4′,5’:5,4]thieno[2,3-e]41,61naphthyridine-8-one derivatives via Pictet-Spengler cyclization is reported. The reaction of 4-(3-aminopyrimido[4,5-d]thieno-2-yl)quinoline-2-ones, which could be obtained from Thorpe -Ziegler isomerization of 4-bromomethylquinoline-2-ones and 5-cyano-1,6-dihydro-4-methyl-2-phenyl-6-thioxopyrimidine, with aromatic aldehydes in the presence of BF3.OEt2 gives pyrimidothieno[1,6]naphthyridines in good yields. (C)2015 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
If you are hungry for even more, make sure to check my other article about 106-49-0, Computed Properties of C7H9N.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem