Chemistry, like all the natural sciences, Application In Synthesis of 4-[4-(4-aminophenoxy)phenoxy]aniline, begins with the direct observation of nature¡ª in this case, of matter.3491-12-1, Name is 4-[4-(4-aminophenoxy)phenoxy]aniline, SMILES is NC1=CC=C(OC2=CC=C(OC3=CC=C(N)C=C3)C=C2)C=C1, belongs to naphthyridines compound. In a document, author is Kobayashi, Kazuhiro, introduce the new discover.
SYNTHESIS OF N,N-DIALKYL-5(or 10)-OXOBENZO[b][1,8 or 1,7(or 1,6)]NAPHTHYRIDINE-10(5H)(or 5(10H))-CARBOTHIOAMIDES BASED ON THE REACTION OF THE RESPECTIVE (CHLOROPYRIDINYL)(2-ISOTHIOCYANATOPHENYL)METHANONES WITH SECONDARY AMINES
The addition of secondary amines to (2-chloropyridin-3-yl)(2-isothiocyanatophenyl)methanone, derived from 2-chloropyridine and N-(2-formylphenyl)formamide, followed by treatment of the resulting thiourea intermediates with sodium hydride has proven to provide a method for the synthesis of N,N-dialky1-5-oxobenzo[b][1,8]naphthyridine-10 (5H)-carbothioamides. Similarly, N,N-dialkyl-5-oxobenzo[b][1,7]naphthyridine-10(5H)-carbothioamides and N,N-dialkyl-10-oxobenzo[b][1,6]naphthyridine-5(10H)-carbothioamides can be prepared from the respective (chloropyridinyl)(2-isothiocyanatophenyl)methanones.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 3491-12-1. Application In Synthesis of 4-[4-(4-aminophenoxy)phenoxy]aniline.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem