Name is 3-Bromo-1,5-naphthyridine, as a common heterocyclic compound, it belongs to naphthyridine compound, and cas is 17965-71-8, its synthesis route is as follows.
7-Bromo-1,5-naphthyridine-1-oxide (6) To a stirring solutionof compound 5 (100 mg, 0.48 mmol) in3 mL CH2Cl2 at 0C was added m-CPBA (142 mg, 0.58 mmol) in portion for 5 min, then at roomtemperature for 2 h. Water (10 mL) was added to quench the reaction, and themixture was extracted with CH2Cl2 (3¡Á10 mL). Thecombined extracts were washed with brine, dried over anhydrous Na2SO4,and concentrated in vacuum. Purification by chromatography (PE/EA = 2:1)provided compound 6 (64 mg, 67%) asa white solid. MP: 151~152C (Ref.2 148~149C). 1H NMR(400 MHz, CDCl3): delta9.26-9.13 (m, 1H), 9.00 (dd, J = 4.7,2.3 Hz, 1H), 8.54 (d, J = 5.8 Hz, 1H),7.98 (d, J = 6.1 Hz, 1H), 7.54 (dd, J = 9.2, 5.2 Hz, 1H).
17965-71-8, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,17965-71-8 ,3-Bromo-1,5-naphthyridine, other downstream synthetic routes, hurry up and to see
Reference£º
Article; Wu, Jing-Fang; Liu, Ming-Ming; Huang, Shao-Xu; Wang, Yang; Bioorganic and Medicinal Chemistry Letters; vol. 25; 16; (2015); p. 3251 – 3255;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem