5174-90-3, Name is Ethyl 2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate, belongs to naphthyridine compound, is a common compound. Computed Properties of C11H10N2O3In an article, once mentioned the new application about 5174-90-3.
ONO Pharmaceutical Co., Ltd.; INUKAI, Takayuki; TAKEUCHI, Jun; YASUHIRO, Tomoko; WOLF, Mark Allan; PAWAR, Vijay Dattaram; CHAKRABARTI, Anjan; CHITTIMALLA, Santhosh Kumar
The compound represented by general formula (I) has strong Axl inhibition activity by means of a pyridone ring structure being introduced into a pyrrolo pyrimidine skeleton, and so the result can serve as a treatment agent for Axl-related diseases, for example cancers such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glial tumors, renal disease, immune system disorders, and cardiovascular disease.
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Reference£º
1,612-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N606 – PubChem