In heterogeneous catalysis, the catalyst is in a different phase from the reactants. COA of Formula: C12H8ClFN2O3, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 100361-18-0, name is 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid. In an article£¬Which mentioned a new discovery about 100361-18-0
HETERO DRUGS LIMITED
The present invention provides a novel process for the preparation of gemifloxacin and its pharmaceutically acceptable acid addition salts in high yield. The present invention also relates to novel polymorphs of gemifloxacin free base and its hydrates to the processes for their preparation and to pharmaceutical compositions comprising them. The present invention also relates to infusion solutions of gemifloxacin and to processes for their preparation. Thus, 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphth- yridine-3-carboxylic acid is reacted with a mixture of acetic anhydride, acetic acid and boric acid to give borane compound, which is then treated with 4-Aminomethyl-3-methoxyimino-pyrrolidinium dimethanesulfonate in presence of triethylamine, followed by treatment with 3.5% sodium hydroxide solution to give gemifloxacin free base.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 100361-18-0, help many people in the next few years.COA of Formula: C12H8ClFN2O3
Reference£º
1,695-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N689 – PubChem