One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, SDS of cas: 5423-54-1, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 5423-54-1, Name is 1,5-Naphthyridin-4-ol, molecular formula is C8H6N2O
SB-334867 has been an important ligand for the study of the orexin 1 (OX1) receptor due to its high OX1/OX2 selectivity and bioavailability. This ligand however, contains a 2-methylbenzoxazole ring system which is known to undergo hydrolysis, particularly under acidic or basic conditions. The possibility that SB-334867 would be susceptible to significant hydrolysis was evaluated in various formulations and in the solid state. SB-334867 was found to be unstable under conditions commonly employed to prepare stock solutions for in vitro and in vivo studies. In addition, and most alarmingly, the hydrochloride salt of SB-334867 was found to quantitatively decompose to an OX1-inactive product even in the solid state. These findings combine to suggest that studies using SB-334867 (and any other 2-methylbenzoxazole-containing compound) should be performed with great care to avoid the confounding effects of the rapid hydrolytic decomposition of this susceptible structure.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. SDS of cas: 5423-54-1, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 5423-54-1, in my other articles.
Reference£º
1,398-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N392 – PubChem