Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. category: naphthyridine. Introducing a new discovery about 254-60-4, Name is 1,8-Diazanaphthalene
The rates of aminolyses of p-toluenesulfonyl chloride with primary and tertiary amines have been determined both in acetonitrile and in ethanol.The Broensted plots of log krel again pKa’ values fo amines (except hydrazine and 1,8-naphthyridine in acetonitrile) gave a good correlation when the aminolyses were carried out in acetonitrile.In ethanol, however, although Broensted plots with all tertiary amines show a good correlation, less basic hydrazine shows a higher reactivity than n-butylamine.The abnormal rate enhancement found with hydrazine is undoubtedly due to the alpha-effect, while with 1,8-naphthyridine in acetonitrile is considered to be due to the repulsion of two lone electron pairs on the two nitrogen atoms in 1,8-naphthyridine.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.category: naphthyridine, you can also check out more blogs about254-60-4
Reference£º
1,210-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N204 – PubChem