Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, the author is Feng, Lian-Shun and a compound is mentioned, 100361-18-0, 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid, introducing its new discovery. 100361-18-0
The synthesis of naphthyridone derivatives containing 8-alkoxyimino-1,6- dizaspiro[3.4]octane scaffolds, the position isomers of the side chain at the C-7 position of Zabofloxacin, has been achieved in eight steps from tert-butyl 3-cyano-4-oxopyrrolidine-1-carboxylate. The possible reaction mechanisms were also proposed. The key spirocyclic carbamate esters, which could be prepared using a modified Hofmann rearrangement strategy, were condensed with naphthyridone nuclei, and the resulting condensates were easily cleaved by TMSI and subsequently cyclized in the presence of K2CO3. Moreover, additional N-methylation derivatives were also obtained using the synthetic sequence.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! Read on for other articles about 13691-36-6!, 100361-18-0
Reference£º
1,717-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N711 – PubChem