254-60-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Chapter, the author is Gibbs, Neil K. and a compound is mentioned, 254-60-4, 1,8-Diazanaphthalene, introducing its new discovery.
Drug-induced skin phototoxicity is a well recognised cause of abnormal skin photosensitivity. This chapter gives a general overview of the history, the range of drugs and the types of skin reactions associated with photoxicity. The fluoroquinolone antibiotics have become the most important group of pharmaceutical phototoxins of the last decade. The response of regulatory authorities to the finding that fluoroquinolones photosensitise skin carcinogenesis in mice has led to increased examination of phototoxic potential during drug development. The validation of simple in vitro screening methods and an increased knowledge of structure-phototoxic activity relationships may, in the future, lead to a reduced number of phototoxic drugs reaching the market.
Interested yet? Keep reading other articles of 2682-49-7!, 254-60-4
Reference£º
1,120-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N114 – PubChem