215523-34-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1,8-Naphthyridine-2-carboxylic acid, cas is 215523-34-5,the naphthyridine compound, it is a common compound, a new synthetic route is introduced below.
14.00 mmol of corresponding amino derivative and 10.00 mmol of carboxylic acid, 11.00 mmol of 1-hydroxybenzotriazole and 11.10 mmol of N’-(3-dimethylaminopropyl)-N-ethylcarbodiimid hydrochlorid in 120 cm3 N,N dimethylformamide was stirred overnight at room temperature. Then 1000 g of crashed ice was added and stirred further one hour. The precipitate was filtered off, washed with saturated NaHCO3 solution, water and dried at room temperature. The crude material was refluxed in ethylalcohol for 10 minutes, cooled back and filtered off.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1,8-Naphthyridine-2-carboxylic acid, 215523-34-5
Reference£º
Patent; Klebl, Bert; Baumann, Matthias; Hoppe, Edmund; Brehmer, Dirk; Daub, Henrik; Keri, Gyorgy; Varga, Zoltan; Marosfalvi, Jeno; Orfi, Laszlo; US2008/187575; (2008); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem