As a common heterocyclic compound, it belong naphthyridine compound,7-Chloro-1,8-naphthyridin-2-ol,15944-34-0,Molecular formula: C8H5ClN2O,mainly used in chemical industry, its synthesis route is as follows.,15944-34-0
A mixture of 7-chloro-l,8-naphthyridin-2(lH)-one (52-1) (1.26 g, 7 mmol) and cesium carbonate (4.56 g, 14 mmol) was stirred at 115 C overnight. The mixture was diluted with methanol (6 mL) and purified by reverse phase column chromatography (acetonitrile : water = 17:83, with 0.01% NH4OH) to afford compound 52-2 (1.15 g, 70% yield) as a light yellow solid. MS (ESI): m/z 235 [M+H]+.
With the synthetic route has been constantly updated, we look forward to future research findings about 7-Chloro-1,8-naphthyridin-2-ol,belong naphthyridine compound
Reference£º
Patent; SUNOVION PHARMACEUTICALS INC.; JONES, Phillip, G.; LEW, Robert; SPEAR, Kerry, L.; XIE, Linghong; WO2013/169964; (2013); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem