The important role of 254-79-5

With the complex challenges of chemical substances, we look forward to future research findings about 1,5-Naphthyridine

Name is 1,5-Naphthyridine, as a common heterocyclic compound, it belongs to naphthyridine compound, and cas is 254-79-5, its synthesis route is as follows.,254-79-5

Preparation 63-Bromo-[1 ,5]naphthyridine[00123] [1 ,5]Naphthyridine (200 mg, 1.53 mmol) is dissolved in 2 ml_ of acetic acid, sodium acetate (300 mg, 3.07 mmol) is added, the mixture is heated to 85 0C and a solution of bromine (0.087 ml_, 270 mg, 1.69 mmol) in 0.3 ml_ acetic acid is added dropwise. The mixture is heated for 3 h, cooled and evaporated to dryness. The residue is purified by flash column chromatography to give 65 mg of title compound along with dibrominated product.

With the complex challenges of chemical substances, we look forward to future research findings about 1,5-Naphthyridine

Reference£º
Patent; MERZ PHARMA GMBH & CO. KGAA; HENRICH, Markus; WEIL, Tanja; HECHENBERGER, Mirko; MUeLLER, Sibylle; KAUSS, Valerjans; ZEMRIBO, Ronalds; ERDMANE, Elina; SMITS, Gints; WO2011/15343; (2011); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem