Name is 1,7-Naphthyridin-2(1H)-one, as a common heterocyclic compound, it belongs to naphthyridine compound, and cas is 54920-82-0, its synthesis route is as follows.,54920-82-0
To 1,7-naphthyridine-2(1H)-one (CAS registration No.: 54920-82-0) (900 mg), ethanol (20 mL) and benzylbromide (0.8 mL) were added. The resulting mixture was heated and stirred at 80¡ãC for 18 hours. The resulting mixturewas cooled to 0¡ãC, and then sodium borohydride (1100 mg) was added thereto. The resulting product was stirred at0¡ãC for 10 minutes, and then hydrochloric acid was added thereto. The resulting mixture was stirred at room temperaturefor 90 minutes. The resulting product mixture was neutralized with sodium hydroxide, and then ethyl acetate was addedto extract the organic layer. The organic layer was extracted. The organic layer was washed with a saturated salinesolution, and then dried over anhydrous sodium sulfate, and the solvent was removed by evaporation under reducedpressure. Thereafter, the resulting solid was washed with ethyl acetate to obtain the title compound (900 mg) havingthe following physical property values.1H-NMR (CD3OD): delta 2.66, 2.80, 3.45, 3.75, 6.40, 7.29-7.44
With the complex challenges of chemical substances, we look forward to future research findings about 1,7-Naphthyridin-2(1H)-one
Reference£º
Patent; ONO Pharmaceutical Co., Ltd.; INUKAI, Takayuki; TAKEUCHI, Jun; YASUHIRO, Tomoko; WOLF, Mark Allan; PAWAR, Vijay Dattaram; CHAKRABARTI, Anjan; CHITTIMALLA, Santhosh Kumar; (85 pag.)EP3067356; (2016); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem