As a common heterocyclic compound, it belongs to naphthyridine compound, name is 1,8-Naphthyridine-2-carboxylic acid, and cas is 215523-34-5, its synthesis route is as follows.,215523-34-5
To a solution OF 4- [ (4-BROMOPHENYL) (ethoxyimino) methyl]-1-(4-methyl-4- piperidinyl) piperidine (50 mg, 0.12 MMOL), 1, 8-naphthyridine-2-carboxylic acid (25 mg, 0.14 MMOL), and Et3N (44 mg, 0.43 MMOL) in DMF (3 mL, anhydrous) was added HATU (60 mg, 0.16 MMOL) at room temperature. After 16 h the reaction mixture was poured into ice water, and the solid was collected by filtration. The solid was dissolved in CH2CI2 and dried over NA2S04. Concentration in vacuo, and purification by preparative TLC (CH2CI2-MEOH, 9: 1) afforded the title compound as a light brown powder. MS: 564 (M+).
With the complex challenges of chemical substances, we look forward to future research findings about 215523-34-5,belong naphthyridine compound
Reference£º
Patent; SCHERING AKTIENGESELLSCHAFT; WO2004/113323; (2004); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem