Name is 3-Bromo-1,5-naphthyridine, as a common heterocyclic compound, it belongs to naphthyridine compound, and cas is 17965-71-8, its synthesis route is as follows.,17965-71-8
Example 251; The compound obtained in Example 250 (50 mg) was dissolved in acetonitrile (1.5 ml), the solution was added with 3-bromo-1,5- naphthyridine (21.1 mg) obtained by the method described in the literature (Journal of Organic Chemistry, 1968, vol. 33, p.1384), tetrakistriphenylphosphine palladium (3.9 mg) and triethylamine (0.3 ml), and the mixture was stirred at 80C for 4 hours. The reaction mixture was concentrated under reduced pressure, and the resulting residue was purified by silica gel column chromatography (hexane:acetone:triethylamine = 10:10:0.2) to obtain the compound shown in Table 10 (26.8 mg).
With the complex challenges of chemical substances, we look forward to future research findings about 3-Bromo-1,5-naphthyridine
Reference£º
Patent; TAISHO PHARMACEUTICAL CO., LTD; Meiji Seika Kaisha Ltd.; EP1985620; (2008); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem