Downstream synthetic route of 197507-59-8

As the paragraph descriping shows that 197507-59-8 is playing an increasingly important role.

197507-59-8, 1,6-Naphthyridine-2-carboxylic acid is a naphthyridine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution OF 4- [ (4-BROMOPHENYL) (ethoxyimino) methyl]-1- (4-methyl-4-piperidinyl)- piperidine (50mg, 0. 12MMOL), 1, 6-naphthyridine-2-carboxylic acid (25mg, 0. 14MMOL), Et3N (44 mg, 0. 43MMOL) in DMF (3 mL, anhydrous) was added HATU (60mg, 0. 16MMOL) at room temperature. After 16 h the reaction mixture was poured into ice water, and the solid was collected by filtration. The solid was dissolved in CH2CI2, and dried over NA2SO4. CONCENTRATION in vacuo, and purification by preparative TLC (CH2CI2-MEOH, 9: 1) afforded the title compound as a light yellow powder. MS: 564 (M+).

As the paragraph descriping shows that 197507-59-8 is playing an increasingly important role.

Reference£º
Patent; SCHERING AKTIENGESELLSCHAFT; WO2004/113323; (2004); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem