35192-05-3, 2-Chloro-1,7-naphthyridine is a naphthyridine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step B: Preparation of [N- (4-TERT-BUTYL-PHENYL)-2- ( [1, 7]] naphthyridin-2-ylamino)-benzamide A mixture of [2-AMINO-N- (4-TERT-BUTYL-PHENYL)-BENZAMIDE] (Step A, 163 mg, 0.61 mmol), [2-CHLORO- [1,] 7] naphthyridine [(100] mg, 0.61 [MMOL),] [PD2 (DBA)] 3 (6.0 mg, 0. [006] mmol), 2- dicyclohexyl [PHOSPHINO-2′- (N-N-DIMETHYAMINO)] biphenyl (6.0 mg, 0.015 mmol), and LiN (TMS) 2 (1 M solution in THF, 2.3 mL) was heated at [80 C] for 12 h in a sealed tube. The mixture was concentrated in vacuo and the crude material was purified with flash chromatography [(SI02,] [20%] EtOAc/hexane) and crystallization from EtOH to give the desired compound. MS [(ES+)] : [397.] 0 (M+H) [+.] Calc’d for [C25H24N4O-396.] 48.
As the paragraph descriping shows that 35192-05-3 is playing an increasingly important role.
Reference£º
Patent; AMGEN INC.; WO2004/5279; (2004); A2;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem